2016 FINA World Swimming Championships (25 m) – Women's 4 × 50 metre medley relay

The Women's 4 × 50 metre medley relay competition of the 2016 FINA World Swimming Championships (25 m) was held on 7 December 2016.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were held at 09:30.

Final
The final was held at 18:30.