2016 French Open – Wheelchair women's singles

Marjolein Buis defeated Sabine Ellerbrock in the final, 6–3, 6–4 to win the women's singles wheelchair tennis title at the 2016 French Open.

Jiske Griffioen was the defending champion, but was defeated in the quarterfinals by Jordanne Whiley.

Seeds
• # Jiske Griffioen (quarterfinals)

• # 🇯🇵 Yui Kamiji (semifinals)