2016 Gerry Weber Open – Singles

Roger Federer was the three-time defending champion, but lost in the semifinals to Alexander Zverev.

Florian Mayer won the title, defeating Zverev in the final, 6–2, 5–7, 6–3.

Seeds
• # Roger Federer (semifinals)

• #🇯🇵 Kei Nishikori (second round, withdrew)

• #🇦🇹 Dominic Thiem (semifinals)

• #🇨🇿 Tomáš Berdych (first round)

• #🇧🇪 David Goffin (quarterfinals)

• #🇪🇸 David Ferrer (first round)

• #🇷🇸 Viktor Troicki (first round)

• #🇩🇪 Philipp Kohlschreiber (quarterfinals, withdrew)

Seeds
• # Ernests Gulbis (qualified)

• # 🇺🇿 Denis Istomin (first round)

• # 🇨🇿 Lukáš Rosol (first round)

• # 🇺🇸 Rajeev Ram (qualifying competition)

• # 🇺🇦 Illya Marchenko (first round)

• # Robin Haase (qualifying competition)

• # 🇺🇦 Sergiy Stakhovsky (qualified)

• # Nikoloz Basilashvili (first round)

Qualifiers
• # Ernests Gulbis

• # 🇩🇪 Benjamin Becker

• # 🇯🇵 Yūichi Sugita

• # 🇺🇦 Sergiy Stakhovsky