2016 Heilbronner Neckarcup – Singles

Alexander Zverev was the defending champion, but chose not to defend his title.

Nikoloz Basilashvili won the title after defeating Jan-Lennard Struff 6–4, 7–6(7–3) in the final.

Seeds
• # 🇱🇹 Ričardas Berankis (first round)

• # 🇦🇷 Horacio Zeballos (first round)

• # 🇪🇸 Albert Montañés (semifinals)

• # 🇪🇸 Daniel Muñoz de la Nava (first round)

• # 🇯🇵 Yoshihito Nishioka (first round)

• # 🇩🇪 Jan-Lennard Struff (final)

• # 🇩🇪 Dustin Brown (first round)

• # Igor Sijsling (quarterfinals)