2016 Howard Bison football team

The 2016 Howard Bison football team represented Howard University as a member of the Mid-Eastern Athletic Conference (MEAC) during the 2016 NCAA Division I FCS football season. Led by Gary Harrell in his fifth and final season as head coach, the Bison compiled an overall record of 2–9 with a mark of 2–6, placing tenth in the MEAC. Howard played home games at William H. Greene Stadium in Washington, D.C.

Harrell's contract was renewed after the season. He finished his tenure at Howard with a record of 20–36.