2016 Kuurne–Brussels–Kuurne

The 68th edition of the Kuurne–Brussels–Kuurne cycling classic was held on 28 February 2016. It was part of the 2016 UCI Europe Tour and ranked as a 1.HC event. It was the second and concluding race of the Belgian opening weekend, the year's first road races in Northwestern Europe, one day after Omloop Het Nieuwsblad.

Belgian Jasper Stuyven won the race after a 17 km solo. The route was 200.7 km, starting and finishing in Kuurne. 199 riders started and 97 riders finished the race.