2016 Manila Challenger – Singles

2nd seed Mikhail Youzhny won his fifth career ATP Challenger Tour title, beating Marco Chiudinelli 6–4, 6–4. This was Youzhny's third consecutive ATP Challenger title, having won the KPN Bangkok Open and the KPN Bangkok Open II in the previous two weeks.

Seeds
• # 🇮🇹 Luca Vanni (second round)

• # 🇷🇺 Mikhail Youzhny (champion)

• # 🇸🇰 Lukáš Lacko (semifinals)

• # 🇯🇵 Go Soeda (semifinals)

• # 🇧🇪 Kimmer Coppejans (second round)

• # 🇮🇹 Thomas Fabbiano (second round)

• # Igor Sijsling (quarterfinals)

• # 🇮🇳 Somdev Devvarman (first round)