2016 Memphis Open – Singles

Three-time defending champion Kei Nishikori successfully defended his title, defeating Taylor Fritz in the final, 6–4, 6–4 to win the singles title at the 2016 Memphis Open. Notably, this was only Fritz' third career event on the ATP Tour.

Seeds
The top four seeds receive a bye into the second round. • #🇯🇵 Kei Nishikori (champion)

• #🇺🇸 Steve Johnson (second round)

• #🇺🇸 Donald Young (quarterfinals)

• #🇺🇸 Sam Querrey (semifinals)

• #🇺🇸 Denis Kudla (second round)

• #🇦🇺 Sam Groth (first round)

• #🇦🇺 John Millman (second round)

• #🇧🇦 Damir Džumhur (second round)

Seeds
• # 🇲🇩 Radu Albot (qualifying competition)

• # 🇺🇸 Bjorn Fratangelo (qualifying competition)

• # 🇯🇵 Yoshihito Nishioka (qualified)

• # 🇯🇵 Tatsuma Ito (first round)

• # 🇦🇺 John-Patrick Smith (first round)

• # 🇺🇸 Dennis Novikov (first round)

• # 🇺🇸 Jared Donaldson (qualified)

• # 🇪🇸 Adrián Menéndez-Maceiras (qualifying competition)

Qualifiers
• # Henri Laaksonen

• # 🇺🇸 Michael Mmoh

• # 🇯🇵 Yoshihito Nishioka

• # 🇺🇸 Jared Donaldson