2016 Milex Open – Singles

Damir Džumhur was the defending champion, but chose to participate in the 2016 Memphis Open instead.

Guido Andreozzi won the title, defeating Nicolás Kicker 6–0, 6–4 in the final.

Seeds
• #🇩🇴 Víctor Estrella Burgos (second round)

• #🇦🇷 Horacio Zeballos (first round)

• #🇦🇹 Gerald Melzer (second round)

• #🇪🇸 Roberto Carballés Baena (quarterfinals)

• #🇸🇰 Andrej Martin (quarterfinals)

• #🇨🇴 Alejandro González (first round)

• #🇧🇷 André Ghem (first round)

• #🇧🇷 João Souza (second round)