2016 Nottingham Open – Men's singles

Denis Istomin was the defending champion, but lost in the first round to Damir Džumhur.

Steve Johnson won the title defeating Pablo Cuevas in the final, 7–6(7–5), 7–5.

Seeds
All seeds receive a bye into the second round. • Kevin Anderson (quarterfinals)

• Pablo Cuevas (final)

• João Sousa (second round)

• 🇺🇦 Alexandr Dolgopolov (quarterfinals)

• 🇺🇸 Sam Querrey (third round)

• 🇺🇸 Steve Johnson (champion)

• 🇮🇹 Andreas Seppi (semifinals)

• 🇱🇺 Gilles Müller (semifinals)

• 🇨🇾 Marcos Baghdatis (quarterfinals)

• 🇪🇸 Pablo Carreño Busta (second round)

• 🇨🇦 Vasek Pospisil (third round)

• 🇮🇹 Paolo Lorenzi (second round)

• 🇦🇷 Guido Pella (second round)

• 🇪🇸 Fernando Verdasco (third round)

• 🇰🇿 Mikhail Kukushkin (second round)

• 🇱🇹 Ričardas Berankis (second round)

Seeds
• # 🇫🇷 Stéphane Robert (qualified)

• # 🇦🇺 Sam Groth (qualifying competition)

• # Marcelo Arévalo (first round)

• # 🇮🇳 Ramkumar Ramanathan (first round)

• # 🇦🇺 Matthew Barton (qualifying competition)

• # 🇺🇸 Ernesto Escobedo (qualified)

• # 🇨🇦 Frank Dancevic (qualified)

• # 🇨🇿 Michal Konečný (qualifying competition)

Qualifiers
• # 🇫🇷 Stéphane Robert

• # 🇨🇦 Frank Dancevic

• # 🇺🇸 Ernesto Escobedo

• # 🇨🇿 Jan Hernych