2016 Oklahoma Sooners softball team

The 2016 Oklahoma Sooners softball team represented the University of Oklahoma in the 2016 NCAA Division I softball season. The Sooners were coached by Patty Gasso, who led her twenty-second season. The Sooners finished with a record of 57–8. They played their home games at OU Softball Complex and competed in the Big 12 Conference, where they finished first with a 17–1 record.

The Sooners were invited to the 2016 NCAA Division I softball tournament, where they swept the West Regional and then completed a run through the Women's College World Series to claim the NCAA Women's College World Series Championship.