2016 Open Bogotá – Singles

Eduardo Struvay was the defending champion but lost in the second round to Facundo Bagnis.

Bagnis won the title after defeating Horacio Zeballos 3–6, 6–3, 7–6(7–4) in the final.

Seeds
• # 🇦🇷 Facundo Bagnis (champion)

• # 🇦🇷 Horacio Zeballos (final)

• # 🇪🇸 Íñigo Cervantes (semifinals)

• # 🇨🇴 Santiago Giraldo (semifinals)

• # 🇩🇴 Víctor Estrella Burgos (second round)

• # 🇧🇷 João Souza (second round)

• # 🇧🇪 Arthur De Greef (second round, retired)

• # 🇦🇷 Agustín Velotti (second round, retired)