2016 Open du Pays d'Aix – Singles

Robin Haase was the defending champion but chose not to participate.

Thiago Monteiro won the title, defeating Carlos Berlocq 4–6, 6–4, 6–1 in the final.

Seeds
• # 🇨🇿 Lukáš Rosol (quarterfinals)

• # 🇦🇷 Diego Schwartzman (withdrew)

• # 🇧🇷 Rogério Dutra Silva (quarterfinals)

• # 🇫🇷 Stéphane Robert (first round)

• # 🇩🇪 Mischa Zverev (second round)

• # 🇸🇪 Elias Ymer (semifinals)

• # 🇩🇪 Daniel Brands (first round)

• # 🇦🇷 Máximo González (first round)