2016 Torneo de Mendoza – Singles

Gerald Melzer won his 2nd career ATP Challenger Tour title, beating Axel Michon 4–6, 6–4, 6–0.

Seeds
• # 🇦🇷 Horacio Zeballos (first round)

• # 🇧🇷 Rogério Dutra Silva (first round)

• # 🇪🇸 Roberto Carballés Baena (semifinals)

• # 🇦🇷 Facundo Argüello (first round)

• # 🇦🇷 Facundo Bagnis (semifinals)

• # 🇸🇰 Andrej Martin (first round)

• # 🇦🇷 Máximo González (first round)

• # 🇦🇹 Gerald Melzer (champion)