2016 Western & Southern Open – Women's doubles

Chan Hao-ching and Chan Yung-jan were the defending champions, but lost in the semifinals to Sania Mirza and Barbora Strýcová.

Mirza and Strýcová went on to win the title, defeating Martina Hingis and CoCo Vandeweghe in the final, 7–5, 6–4.

Seeds
The top four seeds received a bye into the second round. • # 🇫🇷 Caroline Garcia / 🇫🇷 Kristina Mladenovic (second round)

• # Chan Hao-ching / Chan Yung-jan (semifinals)

• # 🇭🇺 Tímea Babos / 🇰🇿 Yaroslava Shvedova (quarterfinals)

• # Martina Hingis / 🇺🇸 CoCo Vandeweghe (final)

• # 🇩🇪 Julia Görges / 🇨🇿 Karolína Plíšková (semifinals)

• # 🇺🇸 Raquel Atawo / 🇺🇸 Abigail Spears (quarterfinals)

• # 🇮🇳 Sania Mirza / 🇨🇿 Barbora Strýcová (champions)

• # 🇨🇳 Xu Yifan / 🇨🇳 Zheng Saisai (second round)