2016 Wimbledon Championships – Women's singles

Defending champion Serena Williams defeated Angelique Kerber in the final, 7–5, 6–3 to win the ladies' singles tennis title at the 2016 Wimbledon Championships. It was her seventh Wimbledon singles title and 22nd major singles title overall, equaling Steffi Graf's Open Era record. Williams lost just one set during the tournament, to Christina McHale in the second round.

This was also the first time two women contested multiple major finals in the same season since Amélie Mauresmo and Justine Henin-Hardenne met in the 2006 Australian Open and Wimbledon finals, as Williams and Kerber had contested the 2016 Australian Open final.

This marked the first Wimbledon where no two fellow countrywomen faced off in the first round, meaning no country was guaranteed to have a player in the second round. In addition to Williams and Kerber, Garbiñe Muguruza, Agnieszka Radwańska and Simona Halep were in contention for the world No. 1 ranking. Williams retained the top spot by reaching the fourth round. She also spent her 300th week atop the WTA rankings during the second week of the tournament, and won her 300th major match by defeating Annika Beck in the third round.

At 36 years old, Venus Williams became the oldest woman to reach a major semifinal since Martina Navratilova at the 1994 Wimbledon Championships.

Seeds
• 🇺🇸 Serena Williams (champion)

• 🇪🇸 Garbiñe Muguruza (second round)

• 🇵🇱 Agnieszka Radwańska (fourth round)

• 🇩🇪 Angelique Kerber (final)

• 🇷🇴 Simona Halep (quarterfinals)

• 🇮🇹 Roberta Vinci (third round)

• Belinda Bencic (second round, retired due to a wrist injury)

• 🇺🇸 Venus Williams (semifinals)

• 🇺🇸 Madison Keys (fourth round)

• 🇨🇿 Petra Kvitová (second round)

•  Timea Bacsinszky (third round)

• 🇪🇸 Carla Suárez Navarro (fourth round)

• 🇷🇺 Svetlana Kuznetsova (fourth round)

• 🇦🇺 Samantha Stosur (second round)

• 🇨🇿 Karolína Plíšková (second round)

• 🇬🇧 Johanna Konta (second round)

• 🇺🇦 Elina Svitolina (second round)

• 🇺🇸 Sloane Stephens (third round)

• 🇸🇰 Dominika Cibulková (quarterfinals)

• 🇮🇹 Sara Errani (second round)

• 🇷🇺 Anastasia Pavlyuchenkova (quarterfinals)

• 🇷🇸 Jelena Janković (second round)

• 🇷🇸 Ana Ivanovic (first round)

• 🇨🇿 Barbora Strýcová (third round)

• 🇷🇴 Irina-Camelia Begu (first round)

•  Kiki Bertens (third round)

• 🇺🇸 CoCo Vandeweghe (fourth round)

• 🇨🇿 Lucie Šafářová (fourth round)

• 🇷🇺 Daria Kasatkina (third round)

• 🇫🇷 Caroline Garcia (second round)

• 🇫🇷 Kristina Mladenovic (first round)

• 🇩🇪 Andrea Petkovic (second round)