2017 Advantage Cars Prague Open – Women's singles

The women's singles of the 2017 Advantage Cars Prague Open tournament was played on clay in Prague, Czech Republic.

Antonia Lottner was the defending champion, but chose not to participate.

Markéta Vondroušová won the title, defeating Karolína Muchová in the final, 7–5, 6–1.

Seeds
• # 🇨🇿 Markéta Vondroušová (champion)

• # Richèl Hogenkamp (second round, withdrew)

• # 🇨🇿 Denisa Allertová (semifinals)

• # 🇷🇺 Irina Khromacheva (second round)

• # 🇷🇴 Mihaela Buzărnescu (first round)

• # 🇨🇿 Lucie Hradecká (first round)

• # Dalila Jakupović (first round)

• # 🇸🇰 Rebecca Šramková (first round)