2017 Memphis Open – Singles

Kei Nishikori was the four-time defending champion, but chose to compete in Buenos Aires instead.

Ryan Harrison won his first ATP World Tour singles title, defeating Nikoloz Basilashvili in the final, 6–1, 6–4. This was the first time in the tournament's 41-year history that no seeded players reached the semifinals. It was also the first ATP tour level event where this happened since 2013 at Nice.

Seeds
The top four seeds receive a bye into the second round. • # Ivo Karlović (second round)

• #🇺🇸 John Isner (quarterfinals)

• #🇺🇸 Sam Querrey (second round)

• #🇺🇸 Steve Johnson (quarterfinals)

• #🇦🇺 Bernard Tomic (first round)

• #🇫🇷 Adrian Mannarino (first round)

• #🇧🇪 Steve Darcis (second round)

• # Lu Yen-hsun (first round)

Seeds
• # 🇨🇦 Peter Polansky (qualified)

• # 🇩🇪 Benjamin Becker (qualifying competition, lucky loser)

• # 🇺🇸 Denis Kudla (first round)

• # Darian King (qualified)

• # 🇸🇪 Elias Ymer (first round)

• # 🇺🇸 Tim Smyczek (qualified)

• # 🇯🇵 Tatsuma Ito (qualifying competition, retired)

• # 🇦🇺 Matthew Barton (qualifying competition)

Qualifiers
• # 🇨🇦 Peter Polansky

• # 🇺🇸 Tim Smyczek

• # 🇦🇺 Matthew Ebden

• # Darian King

Lucky loser

 * 1) 🇩🇪 Benjamin Becker