2017 Uruguay Open – Singles

Diego Schwartzman was the defending champion but chose not to defend his title.

Pablo Cuevas won the title after defeating Gastão Elias 6–4, 6–3 in the final.

Seeds
• # Pablo Cuevas (champion)

• # 🇦🇷 Guido Pella (quarterfinals)

• # 🇦🇷 Nicolás Kicker (semifinals)

• # 🇧🇷 Rogério Dutra Silva (quarterfinals)

• # 🇪🇸 Roberto Carballés Baena (second round)

• # 🇮🇹 Marco Cecchinato (first round)

• # Nicolás Jarry (second round)

• # 🇦🇷 Carlos Berlocq (second round)