2018 Brisbane International – Men's singles

Grigor Dimitrov was the defending champion, but lost in the semifinals to Nick Kyrgios.

Kyrgios went on to win the title, defeating Ryan Harrison in the final, 6–4, 6–2.

Seeds
The top four seeds receive a bye into the second round. • # 🇧🇬 Grigor Dimitrov (semifinals)

• # 🇬🇧 Andy Murray (withdrew due to injury)

• # 🇦🇺 Nick Kyrgios (champion)

• # 🇨🇦 Milos Raonic (second round)

• # 🇱🇺 Gilles Müller (first round)

• # 🇦🇷 Diego Schwartzman (first round)

• # 🇧🇦 Damir Džumhur (first round)

• # 🇩🇪 Mischa Zverev (second round)

Seeds
• # 🇰🇿 Alexander Bublik (first round)

• # 🇩🇪 Yannick Hanfmann (qualifying competition; lucky loser)

• # 🇺🇸 Ernesto Escobedo (qualified)

• # 🇫🇷 Quentin Halys (first round)

• # 🇨🇦 Peter Polansky (qualified)

• # 🇦🇹 Sebastian Ofner (qualifying competition)

• # 🇦🇷 Renzo Olivo (first round)

• # 🇸🇰 Jozef Kovalík (qualifying competition)

Qualifiers
• # 🇦🇺 John-Patrick Smith

• # 🇨🇦 Peter Polansky

• # 🇺🇸 Ernesto Escobedo

• # 🇺🇸 Michael Mmoh

Lucky loser

 * 1) 🇩🇪 Yannick Hanfmann