2018 Challenger Ciudad de Guayaquil

The 2018 Challenger Ciudad de Guayaquil was a professional tennis tournament played on clay courts. It was the fourteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Guayaquil, Ecuador between October 29 and November 3, 2018.

Seeds

 * 1 Rankings are as of 22 October 2018.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇵🇪 Nicolás Álvarez
 * 🇪🇨 Emilio Gómez
 * 🇩🇴 José Hernández-Fernández
 * 🇪🇨 Diego Hidalgo

The following player received entry into the singles main draw using a protected ranking:
 * 🇨🇴 Santiago Giraldo

The following players received entry from the qualifying draw:
 * 🇦🇷 Federico Coria
 * Martín Cuevas
 * 🇧🇷 Thiago Seyboth Wild
 * 🇵🇪 Juan Pablo Varillas

The following players received entry as lucky losers:
 * 🇺🇸 Ulises Blanch
 * 🇷🇸 Miljan Zekić

Singles

 * 🇦🇷 Guido Andreozzi def. Pedro Sousa 7–5, 1–6, 6–4.

Doubles

 * 🇦🇷 Guillermo Durán / 🇪🇨 Roberto Quiroz def. 🇧🇷 Thiago Monteiro / 🇧🇷 Fabrício Neis 6–3, 6–2.