2018 Challenger de Buenos Aires – Singles

Nicolás Kicker was the defending champion but was suspended from tennis due to match-fixing.

Pablo Andújar won the title after defeating Pedro Cachin 6–3, 6–1 in the final.

Seeds
• # 🇦🇷 Guido Andreozzi (first round)

• # 🇪🇸 Pablo Andújar (champion)

• # 🇧🇷 Thiago Monteiro (first round)

• # Pedro Sousa (first round, retired)

• # 🇧🇴 Hugo Dellien (second round)

• # 🇦🇷 Carlos Berlocq (first round)

• # 🇮🇹 Gianluigi Quinzi (second round)

• # 🇦🇷 Facundo Bagnis (first round)