2018 Eastbourne International – Men's singles

Novak Djokovic was the defending champion, but chose not to participate this year.

Mischa Zverev won his first ATP singles title, defeating Lukáš Lacko in the final, 6–4, 6–4.

Seeds
The top four seeds received a bye into the second round. • 🇦🇷 Diego Schwartzman (second round)

• 🇬🇧 Kyle Edmund (quarterfinals)

• 🇨🇦 Denis Shapovalov (quarterfinals)

• 🇮🇹 Marco Cecchinato (semifinals)

• 🇦🇷 Leonardo Mayer (second round)

• 🇪🇸 David Ferrer (second round)

• 🇺🇸 Steve Johnson (second round)

• 🇭🇺 Márton Fucsovics (withdrew due to hip injury)

Seeds
• # 🇺🇸 Jack Sock (first round)

• # 🇦🇺 Alex de Minaur (qualified)

• # 🇮🇹 Matteo Berrettini (qualified)

• # 🇬🇧 Jay Clarke (qualifying competition, lucky loser)

• # 🇷🇺 Ivan Nedelko (first round)

• # 🇪🇨 Roberto Quiroz (qualified)

• # 🇩🇪 Jan Choinski (first round)

• # 🇮🇹 Matteo Viola (qualifying competition)

Qualifiers
• # 🇩🇪 Daniel Brands

• # 🇦🇺 Alex de Minaur

• # 🇮🇹 Matteo Berrettini

• # 🇪🇨 Roberto Quiroz

Lucky loser
• # 🇬🇧 Jay Clarke