2018 FINA World Swimming Championships (25 m) – Women's 4 × 50 metre medley relay

The women's 4 × 50 metre medley relay competition of the 2018 FINA World Swimming Championships (25 m) was held on 12 December 2018.

Records
Prior to the competition, the existing world and championship records were as follows.

Heats
The heats were started at 09:30.

Final
The final was held at 19:00.