2018 Internazionali di Tennis Città di Vicenza – Singles

Márton Fucsovics was the defending champion but chose not to defend his title.

Hugo Dellien won the title after defeating Matteo Donati 6–4, 5–7, 6–4 in the final.

Seeds
• # 🇮🇹 Lorenzo Sonego (first round)

• # 🇩🇪 Yannick Maden (first round)

• # 🇦🇹 Sebastian Ofner (second round)

• # 🇧🇴 Hugo Dellien (champion)

• # 🇮🇹 Stefano Travaglia (quarterfinals, retired)

• # 🇩🇪 Matthias Bachinger (first round, retired)

• # 🇦🇺 Jason Kubler (first round)

• # 🇩🇴 Víctor Estrella Burgos (first round)