2018 L'Open 35 de Saint-Malo – Singles

Polona Hercog was the defending champion, but chose not to participate.

Liudmila Samsonova won the title, defeating Katarina Zavatska in the final, 6–0, 6–2.

Seeds
• # 🇩🇪 Carina Witthöft (withdrew)

• # 🇺🇦 Anhelina Kalinina (first round)

• # 🇧🇪 Ysaline Bonaventure (first round, retired)

• # 🇺🇿 Sabina Sharipova (withdrew)

• # 🇩🇪 Laura Siegemund (first round)

• # 🇷🇴 Irina Bara (semifinals)

• # 🇷🇺 Irina Khromacheva (first round)

• # Verónica Cepede Royg (semifinals)

• # 🇱🇮 Kathinka von Deichmann (quarterfinals)

• # 🇨🇿 Tereza Smitková (first round)