2018 Monterrey Challenger – Singles

Maximilian Marterer was the defending champion but chose not to defend his title.

David Ferrer won the title after defeating Ivo Karlović 6–3, 6–4 in the final.

Seeds
• # 🇪🇸 Marcel Granollers (quarterfinals)

• # 🇺🇸 Michael Mmoh (withdrew)

• # 🇮🇹 Paolo Lorenzi (first round)

• # 🇪🇸 Adrián Menéndez Maceiras (first round)

• # Ivo Karlović (final)

• # 🇪🇸 David Ferrer (champion)

• # 🇦🇹 Gerald Melzer (quarterfinals)

• # 🇪🇸 Pedro Martínez (second round)