2018 Monterrey Open – Singles

Anastasia Pavlyuchenkova was the defending champion, but withdrew before the tournament began.

Garbiñe Muguruza won the title, defeating Tímea Babos in the final, 3–6, 6–4, 6–3.

Seeds
• #🇪🇸 Garbiñe Muguruza (champion)

• #🇸🇰 Magdaléna Rybáriková (quarterfinals)

• #🇺🇦 Lesia Tsurenko (second round, withdrew)

• #🇭🇺 Tímea Babos (final)

• # Monica Puig (quarterfinals)

• #🇷🇴 Ana Bogdan (semifinals)

• #🇺🇸 Sachia Vickery (semifinals)

• #🇦🇺 Ajla Tomljanović (quarterfinals)

Seeds
• # 🇧🇪 Ysaline Bonaventure (first round)

• # 🇯🇵 Miyu Kato (second round)

• # 🇮🇹 Jasmine Paolini (qualifying competition)

• # 🇺🇸 Jamie Loeb (second round)

• # 🇦🇺 Lizette Cabrera (first round)

• # Dalila Jakupović (qualified)

• # 🇨🇿 Marie Bouzková (qualified)

• # Conny Perrin (qualifying competition)

Qualifiers
• # Valentini Grammatikopoulou

• # Dalila Jakupović

• # 🇺🇸 Usue Maitane Arconada

• # 🇨🇿 Marie Bouzková