2018 Nottingham Open – Women's singles

Donna Vekić was the defending champion, but lost in the semifinals to Johanna Konta in a rematch of the previous year's final.

Ashleigh Barty won the title, defeating Konta in the final, 6–3, 3–6, 6–4.

Seeds
• # 🇦🇺 Ashleigh Barty (champion)

• # 🇸🇰 Magdaléna Rybáriková (second round)

• # 🇯🇵 Naomi Osaka (semifinals)

• # 🇬🇧 Johanna Konta (final)

• # 🇷🇴 Mihaela Buzărnescu (quarterfinals)

• # Donna Vekić (semifinals)

• # 🇰🇿 Zarina Diyas (first round, retired)

• # 🇮🇹 Camila Giorgi (first round)

Seeds
• # 🇨🇳 Zheng Saisai (qualified)

• # 🇺🇸 Irina Falconi (qualified)

• # 🇦🇺 Lizette Cabrera (qualifying competition)

• # 🇪🇸 Paula Badosa Gibert (qualifying competition)

• # 🇯🇵 Miharu Imanishi (first round)

• # 🇦🇺 Jaimee Fourlis (qualifying competition)

• # 🇮🇳 Ankita Raina (first round)

• # 🇷🇴 Elena-Gabriela Ruse (qualified)

• # 🇬🇧 Katie Swan (qualified)

• # 🇺🇸 Danielle Lao (qualified)

• # 🇷🇺 Valeria Savinykh (qualified)

• # 🇦🇺 Abbie Myers (first round)

Qualifiers
• # 🇨🇳 Zheng Saisai

• # 🇺🇸 Irina Falconi

• # 🇷🇺 Valeria Savinykh

• # 🇬🇧 Katie Swan

• # 🇷🇴 Elena-Gabriela Ruse

• # 🇺🇸 Danielle Lao