2018 Open Città della Disfida – Singles

Aljaž Bedene was the defending champion but chose not to defend his title.

Marco Trungelliti won the title after defeating Simone Bolelli 2–6, 7–6(7–4), 6–4 in the final.

Seeds
• # 🇮🇹 Marco Cecchinato (first round)

• # Gastão Elias (second round)

• # 🇮🇹 Stefano Travaglia (first round)

• # Pedro Sousa (first round)

• # 🇩🇪 Yannick Maden (second round)

• # 🇸🇰 Martin Kližan (second round, retired)

• # 🇪🇸 Marcel Granollers (first round, retired)

• # 🇸🇰 Jozef Kovalík (withdrew)

• # 🇮🇹 Lorenzo Sonego (second round)