2018 Open du Pays d'Aix – Singles

Frances Tiafoe was the defending champion but chose not to defend his title.

John Millman won the title after defeating Bernard Tomic 6–1, 6–2 in the final.

Seeds
• # 🇦🇺 John Millman (champion)

• # 🇫🇷 Jérémy Chardy (first round)

• # 🇲🇩 Radu Albot (first round)

• # 🇬🇧 Cameron Norrie (second round)

• # 🇫🇷 Calvin Hemery (first round)

• # 🇨🇦 Peter Polansky (first round)

• # 🇺🇦 Sergiy Stakhovsky (first round)

• # 🇧🇷 Thiago Monteiro (quarterfinals)