2018 Puerto Vallarta Open – Singles

This was the first edition of the tournament.

Adrián Menéndez Maceiras won the title after defeating Danilo Petrović 1–6, 7–5, 6–3 in the final.

Seeds
• # 🇪🇸 Adrián Menéndez Maceiras (champion)

• # 🇩🇴 Víctor Estrella Burgos (second round)

• # 🇺🇸 Kevin King (semifinals)

• # 🇺🇸 Christopher Eubanks (first round)

• # 🇷🇸 Danilo Petrović (final)

• # 🇺🇸 Alexander Sarkissian (second round)

• # 🇩🇴 José Hernández-Fernández (second round, retired)

• # 🇪🇨 Roberto Quiroz (quarterfinals)