2018 Queen's Club Championships – Singles

Marin Čilić defeated Novak Djokovic in the final, 5–7, 7–6(7–4), 6–3 to win the singles tennis title at the 2018 Queen's Club Championships. He saved a championship point in the second set. This was Djokovic's first ATP Tour final in almost a year, and Čilić's second victory over Djokovic in their 16 matches played.

Feliciano López was the defending champion, but lost in the quarterfinals to Nick Kyrgios.

Seeds
• # Marin Čilić (champion)

• #🇧🇬 Grigor Dimitrov (second round)

• # Kevin Anderson (first round)

• #🇧🇪 David Goffin (first round)

• #🇺🇸 Sam Querrey (quarterfinals)

• #🇺🇸 Jack Sock (first round)

• #🇬🇧 Kyle Edmund (second round)

• #🇨🇿 Tomáš Berdych (first round)

Seeds
• # 🇫🇷 Julien Benneteau (qualified)

• # 🇦🇺 John Millman (qualified)

• # 🇺🇸 Taylor Fritz (qualifying competition)

• # 🇫🇷 Pierre-Hugues Herbert (first round)

• # 🇮🇳 Yuki Bhambri (qualified)

• # 🇰🇿 Mikhail Kukushkin (first round)

• # 🇷🇴 Marius Copil (qualifying competition)

• # 🇺🇸 Mackenzie McDonald (qualifying competition)

Qualifiers
• # 🇫🇷 Julien Benneteau

• # 🇦🇺 John Millman

• # 🇮🇳 Yuki Bhambri

• # 🇺🇸 Tim Smyczek