2018 Tashkent Challenger – Singles

Guillermo García López was the defending champion but chose not to defend his title.

Félix Auger-Aliassime won the title after defeating Kamil Majchrzak 6–3, 6–2 in the final.

Seeds
• # 🇧🇦 Mirza Bašić (quarterfinals)

• # 🇺🇿 Denis Istomin (quarterfinals)

• # 🇪🇸 Enrique López Pérez (first round)

• # 🇨🇿 Lukáš Rosol (first round, withdrew)

• # 🇷🇺 Alexey Vatutin (second round)

• # 🇵🇱 Kamil Majchrzak (final)

• # 🇩🇪 Daniel Brands (second round)

• # 🇪🇬 Mohamed Safwat (second round)