2019 Abierto Mexicano Telcel – Women's singles

Lesia Tsurenko was the two-time defending champion, but chose not to defend her title.

Wang Yafan won her first WTA singles title, defeating Sofia Kenin in the final, 2–6, 6–3, 7–5.

Seeds
• #🇺🇸 Sloane Stephens (second round)

• #🇺🇸 Danielle Collins (first round)

• # Donna Vekić (semifinals)

• #🇷🇴 Mihaela Buzărnescu (second round)

• #🇺🇸 Sofia Kenin (final)

• # Maria Sakkari (first round)

• #🇨🇳 Zheng Saisai (quarterfinals)

• #🇬🇧 Johanna Konta (quarterfinals)

Seeds
• # 🇷🇺 Irina Khromacheva (first round)

• # 🇧🇪 Ysaline Bonaventure (qualified)

• # 🇺🇸 Christina McHale (qualified)

• # Conny Perrin (qualified)

• # Verónica Cepede Royg (first round)

• # 🇷🇺 Sofya Zhuk (qualifying competition)

• # 🇨🇿 Tereza Martincová (qualifying competition)

• # 🇺🇸 Danielle Lao (first round)

• # 🇦🇺 Kimberly Birrell (first round)

• # 🇦🇺 Astra Sharma (first round)

• # 🇱🇮 Kathinka von Deichmann (first round)

• # 🇮🇹 Martina Trevisan (qualifying competition, lucky loser)

Qualifiers
• # 🇧🇷 Beatriz Haddad Maia

• # 🇧🇪 Ysaline Bonaventure

• # 🇺🇸 Christina McHale

• # Conny Perrin

• # 🇷🇴 Irina Bara

• # 🇷🇺 Varvara Flink

Lucky loser

 * 1) 🇮🇹 Martina Trevisan