2019 Advantage Cars Prague Open – Men's singles

The men's singles of the 2019 Advantage Cars Prague Open tournament was played on clay in Prague, Czech Republic.

Lukáš Rosol was the defending champion but lost in the quarterfinals to Carlos Taberner.

Mario Vilella Martínez won the title after defeating Tseng Chun-hsin 6–4, 6–2 in the final.

Seeds
All seeds receive a bye into the second round. • # 🇸🇰 Andrej Martin (second round)

• # 🇨🇿 Lukáš Rosol (quarterfinals)

• # 🇮🇹 Lorenzo Giustino (quarterfinals)

• # 🇮🇹 Alessandro Giannessi (second round)

• # 🇷🇸 Nikola Milojević (third round)

• # 🇰🇿 Aleksandr Nedovyesov (second round)

• # 🇫🇷 Constant Lestienne (third round)

• # 🇩🇪 Mats Moraing (third round)

• # 🇭🇺 Attila Balázs (third round)

• # 🇧🇷 Rogério Dutra Silva (second round)

• # 🇪🇸 Bernabé Zapata Miralles (quarterfinals)

• # 🇮🇹 Luca Vanni (second round)

• # 🇪🇬 Mohamed Safwat (third round)

• # 🇫🇷 Tristan Lamasine (second round)

• # 🇪🇸 Daniel Gimeno Traver (second round)

• # 🇧🇾 Uladzimir Ignatik (second round)