2019 Australian Open – Wheelchair women's singles

Defending champion Diede de Groot defeated Yui Kamiji in the final, 6–0, 6–2 to win the women's singles wheelchair tennis title at the 2019 Australian Open. It was her third step towards a non-calendar-year Grand Slam.

Seeds
• # Diede de Groot (champion)

• # 🇯🇵 Yui Kamiji (final)