2019 BB&T Atlanta Open – Singles

John Isner was the two-time defending champion and had won the title five times in the last six years, but he lost in the second round to Reilly Opelka. This was only the second time out of ten in the Atlanta Open's history that Isner failed to reach the singles final.

Alex de Minaur won the title, defeating Taylor Fritz in the final, 6–3, 7–6(7–2).

Seeds
The top four seeds received a bye into the second round.

• #🇺🇸 John Isner (second round)

• #🇺🇸 Taylor Fritz (final)

• #🇦🇺 Alex de Minaur (champion)

• #🇫🇷 Pierre-Hugues Herbert (second round)

• #🇺🇸 Frances Tiafoe (first round)

• #🇲🇩 Radu Albot (second round)

• #🇦🇺 Jordan Thompson (first round)

• #🇫🇷 Ugo Humbert (second round)

Seeds
• # 🇵🇱 Kamil Majchrzak (qualified)

• # 🇦🇷 Guido Andreozzi (first round)

• # 🇰🇷 Kwon Soon-woo (qualified)

• # 🇩🇪 Dominik Köpfer (first round)

• # 🇩🇪 Peter Gojowczyk (qualifying competition)

• # Jason Jung (qualified)

• # 🇺🇸 Tommy Paul (qualifying competition)

• # 🇺🇸 Ryan Harrison (qualifying competition, retired)

Qualifiers
• # 🇵🇱 Kamil Majchrzak

• # 🇺🇸 Kevin King

• # 🇰🇷 Kwon Soon-woo

• # Jason Jung