2019 Boar's Head Resort Women's Open – Singles

Mariana Duque Mariño was the defending champion from the 2018 Boar's Head Resort Women's Open tennis tournament, but she had retired from professional tennis earlier in the year.

Whitney Osuigwe won the title, defeating Madison Brengle in the final, 6–4, 1–6, 6–3.

Seeds
• # 🇺🇸 Taylor Townsend (quarterfinals)

• # 🇺🇸 Madison Brengle (final)

• # 🇺🇦 Anhelina Kalinina (quarterfinals)

• # Kaja Juvan (semifinals)

• # 🇦🇺 Kimberly Birrell (first round)

• # 🇺🇸 Francesca Di Lorenzo (first round)

• # 🇺🇸 Claire Liu (first round)

• # 🇺🇸 Whitney Osuigwe (champion)