2019 Brisbane International – Women's singles

Elina Svitolina was the defending champion, but lost to Aliaksandra Sasnovich – in a repeat of the previous year's final – in the second round.

Karolína Plíšková won the title, defeating Lesia Tsurenko in the final, 4–6, 7–5, 6–2.

Seeds
The top two seeds received a bye into the second round. • # 🇺🇦 Elina Svitolina (second round)

• # 🇯🇵 Naomi Osaka (semifinals)

• # 🇺🇸 Sloane Stephens (first round)

• # 🇨🇿 Petra Kvitová (second round)

• # 🇨🇿 Karolína Plíšková (champion)

• # Kiki Bertens (second round)

• # 🇷🇺 Daria Kasatkina (first round)

• # Anastasija Sevastova (quarterfinals)

Seeds
• # 🇷🇸 Aleksandra Krunić (first round)

• # 🇺🇦 Dayana Yastremska (second round, retired)

• # 🇩🇪 Andrea Petkovic (qualifying competition)

• # 🇺🇸 Bernarda Pera (first round)

• # 🇬🇧 Heather Watson (first round)

• # 🇷🇺 Anastasia Potapova (qualified)

• # 🇺🇦 Kateryna Kozlova (second round)

• # 🇱🇺 Mandy Minella (second round)

Qualifiers
• # 🇦🇺 Destanee Aiava

• # 🇷🇺 Anastasia Potapova

• # 🇬🇧 Harriet Dart

• # 🇨🇿 Marie Bouzková