2019 Copa Colsanitas – Singles

Anna Karolína Schmiedlová was the defending champion, but lost in the second round to Beatriz Haddad Maia.

Amanda Anisimova won her first WTA Tour title, defeating Astra Sharma in the final, 4–6, 6–4, 6–1.

Seeds
• # Jeļena Ostapenko (first round)

• # Petra Martić (withdrew)

• #🇩🇪 Tatjana Maria (withdrew)

• #🇸🇰 Anna Karolína Schmiedlová (second round)

• # Tamara Zidanšek (quarterfinals)

• #🇺🇸 Amanda Anisimova (champion)

• #🇪🇸 Sara Sorribes Tormo (quarterfinals)

• #🇵🇱 Magda Linette (second round)

• # Dalila Jakupović (withdrew)

• #🇷🇸 Ivana Jorović (withdrew)

• #🇪🇸 Lara Arruabarrena (semifinals)

Seeds
• # 🇪🇸 Aliona Bolsova (qualified)

• # 🇺🇸 Danielle Lao (first round)

• # Bibiane Schoofs (qualified)

• # 🇮🇹 Martina Trevisan (first round)

• # 🇷🇴 Irina Bara (qualified)

• # 🇺🇸 Francesca Di Lorenzo (qualifying competition, lucky loser)

• # 🇧🇷 Beatriz Haddad Maia (qualified)

• # 🇷🇺 Sofya Zhuk (first round)

• # 🇮🇹 Jasmine Paolini (qualified)

• # 🇺🇸 Kristie Ahn (qualifying competition, lucky loser)

• # 🇩🇪 Anna Zaja (first round)

• # 🇦🇺 Zoe Hives (first round)

Qualifiers
• # 🇪🇸 Aliona Bolsova

• # 🇮🇹 Jasmine Paolini

• # Bibiane Schoofs

• # 🇫🇷 Chloé Paquet

• # 🇷🇴 Irina Bara

• # 🇧🇷 Beatriz Haddad Maia

Lucky losers
• # 🇺🇸 Francesca Di Lorenzo

• # 🇺🇸 Kristie Ahn

• # 🇧🇬 Elitsa Kostova

• # 🇯🇵 Hiroko Kuwata

• # 🇮🇹 Sara Errani