2019 Fergana Challenger – Men's singles

Nikola Milojević was the defending champion but chose not to defend his title.

Emil Ruusuvuori won the title after defeating Roberto Cid Subervi 6–3, 6–2 in the final.

Seeds
All seeds receive a bye into the second round. • # 🇷🇸 Peđa Krstin (second round)

• # 🇫🇷 Gleb Sakharov (quarterfinals)

• # Marc-Andrea Hüsler (second round)

• # 🇹🇷 Cem İlkel (semifinals)

• # 🇮🇳 Sasikumar Mukund (second round)

• # Marcelo Tomás Barrios Vera (third round)

• # 🇷🇺 Pavel Kotov (quarterfinals, retired)

• # Yang Tsung-hua (third round)

• # 🇰🇿 Denis Yevseyev (second round)

• # 🇦🇺 Aleksandar Vukic (quarterfinals)

• # 🇺🇸 Evan King (quarterfinals)

• # 🇩🇴 Roberto Cid Subervi (final)

• # 🇧🇦 Aldin Šetkić (third round)

• # 🇫🇷 Baptiste Crepatte (third round)

• # Alejandro Tabilo (second round)

• # 🇨🇳 Wu Di (third round)