2019 Italian Open – Women's singles

Karolína Plíšková defeated Johanna Konta in the final, 6–3, 6–4 to win the women's singles tennis title at the 2019 Italian Open.

Elina Svitolina was the two-time defending champion, but lost in the second round to Victoria Azarenka.

Naomi Osaka and Simona Halep were in contention for the WTA no. 1 singles ranking at the beginning of the tournament. Osaka retained the top ranking following Halep's loss in the second round.

This was the first Italian Open in 8 years which was not won by neither of Maria Sharapova, Serena Williams or Svitolina.

Seeds
The top eight seeds received a bye into the second round. • 🇯🇵 Naomi Osaka (quarterfinals, withdrew)

• 🇨🇿 Petra Kvitová (third round, retired)

• 🇷🇴 Simona Halep (second round)

• 🇨🇿 Karolína Plíšková (champion)

• 🇺🇦 Elina Svitolina (second round)

• Kiki Bertens (semifinals)

• 🇺🇸 Sloane Stephens (second round)

• 🇦🇺 Ashleigh Barty (third round)

• 🇧🇾 Aryna Sabalenka (first round)

• 🇺🇸 Serena Williams (second round, withdrew)

• Caroline Wozniacki (first round, retired)

• Anastasija Sevastova (first round)

• 🇺🇸 Madison Keys (second round)

• 🇪🇪 Anett Kontaveit (second round)

• 🇨🇳 Wang Qiang (first round)

• 🇩🇪 Julia Görges (second round, retired)

Seeds
• # Maria Sakkari (qualified)

• # 🇺🇸 Amanda Anisimova (qualifying competition, lucky loser)

• # 🇫🇷 Alizé Cornet (qualified)

• # 🇹🇳 Ons Jabeur (qualifying competition)

• # 🇨🇳 Wang Yafan (first round)

• # 🇦🇺 Daria Gavrilova (first round)

• # 🇸🇪 Rebecca Peterson (qualified)

• # 🇷🇺 Ekaterina Alexandrova (first round)

• # 🇩🇪 Tatjana Maria (first round)

• # Monica Puig (qualifying competition)

• # 🇫🇷 Kristina Mladenovic (qualified)

• # 🇷🇺 Margarita Gasparyan (first round, retired)

• # 🇩🇪 Andrea Petkovic (qualifying competition)

• # 🇷🇸 Aleksandra Krunić (first round)

• # Tamara Zidanšek (qualified)

• # 🇫🇷 Pauline Parmentier (first round)

Qualifiers
• # Maria Sakkari

• # 🇫🇷 Kristina Mladenovic

• # 🇫🇷 Alizé Cornet

• # Tamara Zidanšek

• # Polona Hercog

• # 🇷🇴 Irina-Camelia Begu

• # 🇸🇪 Rebecca Peterson

• # 🇩🇪 Mona Barthel

Lucky loser

 * 1) 🇺🇸 Amanda Anisimova