2019 Jacksonville State Gamecocks football team

The 2019 Jacksonville State Gamecocks football team represented Jacksonville State University as a member of the Ohio Valley Conference (OVC) during the 2019 NCAA Division I FCS football season. Led by sixth-year head coach John Grass, the Gamecocks compiled an overall record of 6–6, with a mark of 3–5 conference play, tying for fifth place in the OVC. Jacksonville State played home games at Burgess–Snow Field at JSU Stadium in Jacksonville, Alabama.

Preseason coaches' poll
The OVC released their preseason coaches' poll on July 22, 2019. The Gamecocks were picked to finish in first place.

Preseason All-OVC team
The Gamecocks had seven players at seven positions selected to the preseason all-OVC team.

Offense

Zerrick Cooper – QB

Josh Pearson – WR

Trae Berry – TE

Darius Anderson – OG

Hunter Sosebee – OT

Defense

Jalen Choice – LB

Marlon Bridges – DB