2019 Louisville Cardinals football team

The 2019 Louisville Cardinals football team represented the University of Louisville during the 2019 NCAA Division I FBS football season. This was the team's the first season under head coach Scott Satterfield. The Cardinals played their home games at Cardinal Stadium, formerly known as Papa John's Cardinal Stadium, in Louisville, Kentucky.

Preseason media poll
In the preseason ACC media poll, Louisville was predicted to finish last in the Atlantic Division.