2019 Moldovan National Division

The 2019 Moldovan National Division (Divizia Națională) was the 29th season of top-tier football in Moldova. The season started on 16 March 2019 and ended on 9 November 2019. Sheriff Tiraspol were the defending champions. The winners of the league this season earned a spot in the first qualifying round of the 2020–21 UEFA Champions League, and the second, third and fourth placed clubs earned a place in the first qualifying round of the 2020–21 UEFA Europa League.

Teams
A total of 8 teams will contest the league. These include 7 teams from the 2018 season and one promoted team from the "A" Division: Codru Lozova, making their debut in the top flight. Zaria Bălți were relegated from the Divizia Națională, ending a streak of 13 seasons at the highest level.

Results
Teams will play each other twice (once home, once away).
 * Matches 1−14

Teams will play each other twice (once home, once away).
 * Matches 15−28

Results by round
The following table represents the teams game results in each round.

Relegation play-off
A play-off match was played between the eight-placed team from Divizia Națională and the third-placed team from Divizia A for one place in the next season. The "home" team (for administrative purposes) was determined in a draw held on 12 November 2019.