2019 NCAA Division II women's basketball tournament

The 2019 NCAA Division II women's basketball tournament involved 64 teams playing in a single-elimination tournament to determine the NCAA Division II women's college basketball national champion. It began on March 15, 2019, and concluded with the championship game on March 29, 2019.

The first three rounds were hosted by top-seeded teams in regional play. The eight regional winners met for the quarterfinal and semifinals, better known as the "Elite Eight" and "Final Four" respectively, and National Championship game at Alumni Hall in Columbus, Ohio. In the title game, Lubbock Christian defeated Southwestern Oklahoma State in double overtime to win their second Division II championship.

Atlantic Regional

 * Site: Glenville, West Virginia (Glenville State)

* – Denotes overtime period

Central Regional

 * Site: Hays, Kansas (Fort Hays State)

East Regional

 * Site: Philadelphia, Pennsylvania (USciences)

Midwest Regional

 * Site: O'Reilly Family Event Center, Springfield, Missouri (Drury)

South Regional

 * Site: Lakeland, Florida (Florida Southern)

Southeast Regional

 * Site: Anderson, South Carolina (Anderson (SC))

* – Denotes overtime period

South Central Regional

 * Site: Grand Junction, Colorado (Colorado Mesa)

* – Denotes overtime period

West Regional

 * Site: La Jolla, California (UC San Diego)

Finals
Quarterfinals, semifinals and finals were hosted at Alumni Hall in Columbus, Ohio. Regional winners are reseeded in the quarterfinals.

** – Denotes double-overtime period