2019 Odlum Brown Vancouver Open – Women's singles

Misaki Doi was the defending champion, but lost to Priscilla Hon in the first round.

Heather Watson won the title, defeating Sara Sorribes Tormo in the final, 7–5, 6–4.

Seeds
• # 🇧🇪 Alison Van Uytvanck (first round, retired)

• # 🇯🇵 Misaki Doi (first round)

• # 🇪🇸 Sara Sorribes Tormo (final)

• # 🇧🇪 Ysaline Bonaventure (first round)

• # 🇨🇦 Eugenie Bouchard (first round)

• # 🇬🇧 Heather Watson (champion)

• # 🇺🇸 Varvara Lepchenko (first round)

• # 🇧🇪 Greet Minnen (first round)