2019 Oracle Challenger Series – Houston – Women's singles

Peng Shuai was the defending champion, but chose to compete in an ITF event in Tokyo instead.

Kirsten Flipkens won the title, defeating CoCo Vandeweghe in the final, 7–6(7–4), 6–4. Flipkens beat five American players in five matches on the way to her first WTA 125K series title.

Seeds
All seeds received a bye into the second round. • # 🇺🇸 Danielle Collins (second round)

• # 🇺🇸 Taylor Townsend (quarterfinals)

• # 🇧🇪 Kirsten Flipkens (champion)

• # 🇺🇦 Katarina Zavatska (quarterfinals)

• # 🇷🇴 Patricia Maria Țig (withdrew)

• # 🇺🇸 Caty McNally (quarterfinals)

• # Stefanie Vögele (semifinals)

• # 🇺🇸 Francesca Di Lorenzo (second round, retired)

• # 🇺🇸 Whitney Osuigwe (second round)

• # 🇱🇺 Mandy Minella (quarterfinals)

• # 🇺🇸 Usue Maitane Arconada (third round)

• # 🇺🇸 Allie Kiick (second round)

• # 🇺🇸 Ann Li (third round)

• # 🇺🇸 Caroline Dolehide (third round)

• # 🇺🇸 Sachia Vickery (second round)

• # 🇺🇸 Varvara Lepchenko (second round)

Seeds
• # 🇺🇸 Alexa Glatch (qualifying competition)

• # 🇲🇽 Giuliana Olmos (moved into main draw)

Qualifiers
• # 🇺🇸 Catherine Bellis

• # 🇺🇸 Sophie Chang

Lucky loser
• # 🇺🇸 Kayla Day