2019 Samarkand Challenger – Singles

Luca Vanni was the defending champion but chose not to defend his title.

João Menezes won the title after defeating Corentin Moutet 7–6(7–2), 7–6(9–7) in the final.

Seeds
All seeds receive a bye into the second round. • # 🇫🇷 Corentin Moutet (final)

• # 🇧🇾 Egor Gerasimov (second round)

• # 🇸🇰 Andrej Martin (semifinals)

• # 🇰🇿 Aleksandr Nedovyesov (second round)

• # 🇦🇹 Lucas Miedler (third round)

• # 🇧🇾 Uladzimir Ignatik (quarterfinals)

• # Gonçalo Oliveira (quarterfinals, retired)

• # 🇧🇷 Guilherme Clezar (second round)

• # 🇩🇴 José Hernández-Fernández (quarterfinals)

• # 🇺🇸 Ulises Blanch (third round)

• # 🇷🇺 Roman Safiullin (second round)

• # 🇪🇸 Roberto Ortega Olmedo (quarterfinals)

• # 🇷🇺 Pavel Kotov (third round)

• # 🇩🇴 Roberto Cid Subervi (third round)

• # 🇮🇳 Sumit Nagal (semifinals)

• # Marcelo Arévalo (second round)